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Symbol
Name
ID
Ptch1
patched 1
MGI:105373
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Diabetes mellitus
Anterior hypopituitarism
Panhypopituitarism
Diabetes insipidus
Hypogonadotropic hypogonadism
Disease(s) Associated with PTCH1
holoprosencephaly
holoprosencephaly 7
nevoid basal cell carcinoma syndrome

Mouse Phenotypes
abnormal thymus lobule morphology
thymus hypoplasia
small male preputial gland
small seminal vesicle
cryptorchism
Availability Mouse Genotype
Ptch1mes/Ptch1mes
Ptch1tm1Bjw/Ptch1tm1Bjw
Tg(KRT14-cre)8Brn/0  (conditional)
Ptch1tm1Hahn/Ptch1tm1Hahn
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory